Apply 5 times daily at approx 4 hrly intervals omitting nighttime application. Apply to lesions or impending lesions as soon as possible, preferably during earliest stages (prodrome or erythema). May start during later (papule or blister) stages. Continue for at least 4 days for herpes labialis & 5 days for genital herpes, may be continued for up to 10 days if healing has not occurred.